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Ropinirole Ophthalmic

What is ropinirole ophthalmic?

Ropinirole ophthalmic (Clevor®) is the first FDA-approved drug for inducing vomiting in dogs. On-label directions state that this drug should be administered by veterinary personnel.

Your veterinarian may prescribe this drug off label to use for your dog at home. “Off label” means the drug is being used in a way that has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) or Health Canada.

In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.

How is ropinirole ophthalmic given?

Ropinirole ophthalmic comes as single-use droppers for use in the eye.

This medication should work within 30 minutes. Vomiting typically subsides within 25 minutes of administration. Most dogs vomit 4–5 times after application.

Be careful when administering this drug.

What if I miss giving my pet the medication?

Ropinirole ophthalmic works best when given within 2 hours of ingesting the foreign material or toxin. If you do not give the medication within that time, contact your veterinarian for further advice on the treatment of your dog.

Are there any potential side effects?

Ropinirole ophthalmic may cause the following side effects, which should resolve within 24 hours:

More serious side effects include:

Drug sensitivities can develop over time, with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction each time this medication is used.

Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately.

Ropinirole ophthalmic is a short-acting medication that will stop working within hours.

Are there any risk factors for this medication?

Ropinirole ophthalmic should NOT BE USED in patients who:

This medicine should be USED WITH CAUTION in:

Are there any drug interactions I should be aware of?

Make sure your veterinarian is aware of any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.

Several medications should be used with caution when given with ropinirole ophthalmic, including:

Is any monitoring needed with this medication?

How do I store ropinirole ophthalmic?

What should I do in case of emergency?

© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Created on Sep 16, 2024.

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