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Rivaroxaban

What is rivaroxaban?

Rivaroxaban is an anticoagulant (blood thinner) used to prevent or treat blood clots in cats and dogs.

It is used off label (extra label) in veterinary medicine. Many drugs are commonly prescribed for off-label use in veterinary medicine. “Off label” means the drug is being used in a way that has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) or Health Canada.

In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.

How do I give my pet rivaroxaban?

This medication should take effect within 1 to 2 hours, though effects will not be noticed outwardly.

What if I miss giving my pet the medication?

Contact your veterinarian for further direction if you miss giving a dose. This medication must be dosed carefully: do not give the pet two doses at once or change the dose.

Are there any potential side effects from rivaroxaban?

Rivaroxaban may cause the following side effects:

The following reactions are rare, but if they occur, contact your veterinarian immediately:

Drug sensitivities can develop over time with repeated exposure. Your pet may have no reaction after the first few doses, but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment. Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This short-acting medication will last less than 24 hours, though effects may last longer in pets with kidney or liver disease.

Are there any risk factors for this medication?

DO NOT USE rivaroxaban in pets who:

USE WITH CAUTION in pets who:

Are there any drug interactions I should be aware of?

Certain medications should be USED WITH CAUTION when given with rivaroxaban, including:

Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.

Is any monitoring needed with this medication?

How do I store rivaroxaban?

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Adverse effects should be reported to the FDA or Health Canada.

© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Created on Jan 28, 2025.

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