Rawhide-Based Oral Hygiene Chews

What are rawhide-based oral hygiene chews?

Rawhide-based oral hygiene chews are chews with an abrasive texture that can help prevent or delay the formation of dental plaque and calculus build-up on your pet’s teeth. C.E.T.® Enzymatic Oral Hygiene Chews is one common brand.

The U.S. Food and Drug Administration (FDA) does not review non-drug health products (e.g., herbals, nutraceuticals, shampoos, and other supplements) for safety or effectiveness before they are sold to the public. Manufacturers of non-drug health products must ensure their products are safe and labeled accurately. 

The FDA requires that these non-pharmaceuticals contain a disclaimer that says, “This product is not intended to diagnose, treat, cure or prevent any disease.” Health Canada licenses “veterinary health products” after reviewing safety, efficacy, and manufacturing information provided by the manufacturer. These products are not tested by Health Canada.

Your veterinarian is the best source of information about the safety of non-drug health products in pets. Just because a product is natural does not mean it is safe. All medicines and medicinal plants are potentially toxic if used inappropriately or given at high doses. Supplements can also have side effects, like pharmaceuticals. Few supplements and herbs have been subjected to rigorous scientific trials to determine their efficacy.

Although the information in this handout may be helpful, it may also be incomplete and may not represent the full range of effects the supplement could have on your pet.

How are rawhide-based oral hygiene chews given?

• Rawhide-based oral hygiene chews are given by mouth once daily or as directed by your veterinarian.
• Rawhide-based oral hygiene chews are available in several different sizes; use the appropriate size for the weight and size of your pet.
• In case of human accidental ingestion of this product, call your physician immediately.

This supplement can take several days to show effects within the body. Visible improvements are not always evident.

What if I miss giving my pet the product?

If you miss a dose, give it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once. 

Are there any potential side effects?

Rawhide-based oral hygiene chews may cause the following side effects:

• This supplement is usually well tolerated and adverse reactions are uncommon at recommended doses.
• Be sure to supervise your pet while they are chewing to ensure they do not swallow the chew whole.
• Oral supplements have the potential to cause mild gastrointestinal symptoms such as loose stools, flatulence, and stomach upset. If this occurs, contact your veterinarian. 

Sensitivities can develop over time, with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction each time this medication is used. 

Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. Rawhide-based oral hygiene chews are short-acting supplements that stop working within 24 hours, but effects may be prolonged in pets with liver or kidney disease. 

Are there any risk factors for this supplement?

DO NOT USE rawhide-based oral hygiene chews in pets that:

• Have a known hypersensitivity or allergy to this supplement
• Have not had an oral examination by their veterinarian prior to using this supplement

USE WITH CAUTION in: 

• Pets with moderate to advanced dental disease

Are there any drug interactions I should be aware of?

There are no documented drug interactions with this supplement. Be sure to tell your veterinarian about any medications (including vitamins, supplements or herbal therapies) that your pet is taking before starting any treatment.

Is any monitoring needed with this supplement?

• At home, monitor for any abnormal changes. If any occur, discontinue the supplement and contact your veterinarian. 
• Your veterinarian will let you know when and how they want to reassess your pet to ensure the supplement is working and not causing side effects.  

How do I store rawhide-based oral hygiene chews?

• Keep out of reach of children and other animals.
• Store in the original packaging in a cool, dry place away from direct sunlight and heat.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet's weight and symptoms. Adverse effects should also be reported to the FDA or Health Canada.