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SAMeLQ® is a supplement for dogs and cats that helps support normal liver function. It contains a blend of nutritional ingredients, including:
The U.S. Food and Drug Administration (FDA) does not review non-drug health supplements (e.g., herbals, nutraceuticals, shampoos, and other supplements) for safety or effectiveness before they are sold to the public. Manufacturers of non-drug health supplements must ensure their supplements are safe and labeled accurately.
The FDA requires that these non-pharmaceuticals contain a disclaimer that says, “This supplement is not intended to diagnose, treat, cure or prevent any disease.” Health Canada licenses “veterinary health supplements” after reviewing safety, efficacy, and manufacturing information provided by the manufacturer. These supplements are not tested by Health Canada.
Your veterinarian is the best source of information about the safety of non-drug health supplements in pets. Just because a supplement is natural does not mean it is safe. All medicines and medicinal plants are potentially toxic if used inappropriately or given at high doses. Supplements can also have side effects, like pharmaceuticals. Few supplements and herbs have been subjected to rigorous scientific trials to determine their efficacy.
Although the information in this handout may be helpful, it may also be incomplete and may not represent the full range of effects the supplement could have on your pet.
This supplement can take several days to have full effects on the body, but side effects can occur immediately. Improvements are not always evident, and laboratory tests may be needed to evaluate this supplement’s effectiveness.
If you miss a dose, give it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.
SAMeLQ® may cause the following side effects:
Although not documented in SAMeLQ, oral supplements have the potential to cause mild gastrointestinal symptoms such as loose stools, flatulence and stomach upset. If this occurs, contact your veterinarian.
Sensitivities can develop over time with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment.
Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This supplement should stop working within several days, although effects can be longer in pets with liver or kidney disease.
DO NOT USE SAMeLQ® in:
Contact your veterinarian if your animal's condition does not improve or worsens despite this treatment.
The following medications should be used with caution when given with SAMeLQ:
Be sure to tell your veterinarian about any medications (including vitamins, supplements or herbal therapies) that your pet is taking before starting any treatment.
If you suspect an overdose or an adverse reaction to the supplement/treatment, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet's weight and symptoms. Report any adverse effects to the FDA or Health Canada.
© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Created on May 15, 2025.
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